Dick & me ran into the Delcath team who may be interested in using the new PUMMA database (released at ASCO which they didn't even know about!) which contains full medical history for 5,000+ OM patients pulled together from previous trials and case series.
The Princess Margaret Hospital in Toronto were instrumental in collating this database alongside an international team of MUM researchers. The result is the first full set of Electronic Health Records (EHRs) spanning 25 years of various case series, trial data and other information from a range of specialist centres in ocular melanoma throughout the World. A true example of collaboration across borders.
We are now, via the EMA, trying to put this as the surrogate comparator arm in a number of trials. Fingers crossed if this works out we'll start seeing trials with less people on dreadful control arms.
|Planning how we work the PUMMA dataset into clinical trials|